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Antigenic Specificity | BTLA |
Clone | [11K3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | fluorescein (FITC) conjugate |
Size | 120 tests |
Concentration | 0.25 mg/ml |
Applications | ELISA (EL/EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human CD272 (BTLA). Binds to CD272 on the cell surface of human PBMC in Flow Cytometry and to recombinant CD272-muIg in ELISA. Does not block binding of Biotinylated CD270 (HVEM)-muIg to CD272-muIg in ELISA, but appears to enhance this interaction. Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the Immunoglobulin superfamily and has sequence homology to PD-1 and CTLA4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand, CD270 (HVEM, a TNF superfamily member) can down regulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymo |
Immunogen | Immunogen: Recombinant protein corresponding to soluble human CD272 |
Other Names | BTLA (B- and T-lymphocyte Associated Protein, B- and T-lymphocyte Attenuator, BTLA1, CD272, CD272 Antigen, FLJ16065, MGC129743) (FITC) |
Gene, Accession # | NCBI: AAN71743.1 |
Catalog # | MBS633646 |
Price | $640 |
Order / More Info | BTLA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |