BTLA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBTLA
Clone[11K3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
Formatfluorescein (FITC) conjugate
Size120 tests
Concentration0.25 mg/ml
ApplicationsELISA (EL/EIA), Flow Cytometry (FC/FACS)
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DescriptionRecognizes human CD272 (BTLA). Binds to CD272 on the cell surface of human PBMC in Flow Cytometry and to recombinant CD272-muIg in ELISA. Does not block binding of Biotinylated CD270 (HVEM)-muIg to CD272-muIg in ELISA, but appears to enhance this interaction. Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the Immunoglobulin superfamily and has sequence homology to PD-1 and CTLA4. It is expressed on T and B lymphocytes and other hemopoetic lineages. Engagement of this molecule by its ligand, CD270 (HVEM, a TNF superfamily member) can down regulate activated T and B cell responses. CD272 levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines. Polymo
ImmunogenImmunogen: Recombinant protein corresponding to soluble human CD272
Other NamesBTLA (B- and T-lymphocyte Associated Protein, B- and T-lymphocyte Attenuator, BTLA1, CD272, CD272 Antigen, FLJ16065, MGC129743) (FITC)
Gene, Accession #NCBI: AAN71743.1
Catalog #MBS633646
Price$640
Order / More InfoBTLA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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