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Antigenic Specificity | bcl 10 (NT) (CipER, CLAP) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP (1-6). Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF- B activation (1,2,4,6). Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing (3) and induces apoptosis through caspase-9 activation (3.6). BCL10 exhibits a variety of mutations in MALT lympho |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 5 to 19 of the human BCL-10 protein. |
Other Names | [CIPER; mE10; CARMEN; CLAP], [BCL10; BCL10; CLAP; mE10; CIPER; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10] |
Gene, Accession # | [BCL10], Gene ID: 8915, NCBI: NP_003912.1, UniProt: O95999 |
Catalog # | MBS395915 |
Price | $510 |
Order / More Info | bcl 10 (NT) (CipER, CLAP) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |