bcl 10 (NT) (CipER, CLAP) Antibody from MYBIOSOURCE INC.

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Antigenic Specificitybcl 10 (NT) (CipER, CLAP)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionApoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP (1-6). Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF- B activation (1,2,4,6). Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing (3) and induces apoptosis through caspase-9 activation (3.6). BCL10 exhibits a variety of mutations in MALT lympho
ImmunogenImmunogen: Synthetic peptide corresponding to amino acids 5 to 19 of the human BCL-10 protein.
Other Names[CIPER; mE10; CARMEN; CLAP], [BCL10; BCL10; CLAP; mE10; CIPER; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10]
Gene, Accession #[BCL10], Gene ID: 8915, NCBI: NP_003912.1, UniProt: O95999
Catalog #MBS395915
Price$510
Order / More Infobcl 10 (NT) (CipER, CLAP) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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