SUV4-20H2 (Center), 4-20 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySUV4-20H2 (Center), 4-20
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (predicted reactivity: rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
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DescriptionThis SUV4-20H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids from the Central region of human SUV4-20H2. SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
Immunogenn/a
Other Names[Histone-lysine N-methyltransferase SUV420H2; Lysine N-methyltransferase 5C; Suppressor of variegation 4-20 homolog 2; Su(var)4-20 homolog 2; Suv4-20h2; SUV420H2; KMT5C]
Gene, Accession #[SUV420H2], Gene ID: 84787, NCBI: NP_116090.2, UniProt: Q86Y97
Catalog #MBS9209272
Price$165, $370
Order / More InfoSUV4-20H2 (Center), 4-20 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSouza,P.P., BMC Cell Biol. 10, 41 (2009) Tryndyak,V.P., Cancer Biol. Ther. 5 (1), 65-70 (2006)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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