Phospho-CDKN1A-T145 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-CDKN1A-T145
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThis gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding T145 of human CDKN1A Calculated Molecular Weight: 21kDa
Other Names[Phospho-CDKN1A-T145: P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1], [CDKN1A; CDKN1A; P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; MDA-6]
Gene, Accession #[CDKN1A], Gene ID: 1026, NCBI: P38936.3, UniProt: P38936
Catalog #MBS128383
Price$235, $350, $525
Order / More InfoPhospho-CDKN1A-T145 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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