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Antigenic Specificity | Phospho-CDKN1A-T145 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T145 of human CDKN1A Calculated Molecular Weight: 21kDa |
Other Names | [Phospho-CDKN1A-T145: P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1], [CDKN1A; CDKN1A; P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; MDA-6] |
Gene, Accession # | [CDKN1A], Gene ID: 1026, NCBI: P38936.3, UniProt: P38936 |
Catalog # | MBS128383 |
Price | $235, $350, $525 |
Order / More Info | Phospho-CDKN1A-T145 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |