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Antigenic Specificity | FGFR4 |
Clone | [53CT32.19.3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 κ |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.35 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified recombinant FGFR4 fusion protein was used to produced this monoclonal antibody. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencin |
Immunogen | n/a |
Other Names | [Fibroblast growth factor receptor 4; FGFR-4; CD334; FGFR4; JTK2; TKF] |
Gene, Accession # | [FGFR4], Gene ID: 2264, NCBI: NP_002002.3, UniProt: P22455 |
Catalog # | MBS9200251 |
Price | $165, $370 |
Order / More Info | FGFR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chenodeoxycholate in Females With Irritable Bowel Syndrome-Constipation: A Pharmacodynamic and Pharmacogenetic Analysis. Rao AS, et al. Gastroenterology, 2010 Aug 4. PMID 20691689. Influence of the Fibroblast Growth Factor Receptor 4 Expression and the G388R Functional Polymorphism on Cushing's Disease Outcome. Brito LP, et al. J Clin Endocrinol Metab, 2010 Jul 21. PMID 20660043. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. Ho-Pun-Cheung A, et al. Pharmacogenomics J, 2010 Jul 20. PMID 20644561. FGFR4 transmembrane domain polymorphism and cancer risk: A meta-analysis including 8555 subjects. Xu W, et al. Eur J Cancer, 2010 Jul 16. PMID 20638838. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891. |