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Antigenic Specificity | SIGLEC7 (D-siglec) (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SIGLEC7 (D-siglec) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SIGLEC7 (D-siglec). SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal |
Immunogen | n/a |
Other Names | [Sialic acid-binding Ig-like lectin 7; Siglec-7; Adhesion inhibitory receptor molecule 1; AIRM-1; CDw328; D-siglec; QA79 membrane protein; p75; CD328; SIGLEC7; AIRM1] |
Gene, Accession # | [SIGLEC7], Gene ID: 27036, NCBI: NP_001264130.1, UniProt: Q9Y286 |
Catalog # | MBS9202451 |
Price | $165, $370 |
Order / More Info | SIGLEC7 (D-siglec) (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Nicoll, G., et al., Eur. J. Immunol. 33(6):1642-1648 (2003). Alphey, M.S., et al., J. Biol. Chem. 278(5):3372-3377 (2003). Angata, T., et al., Glycobiology 10(4):431-438 (2000). Falco, M., et al., J. Exp. Med. 190(6):793-802 (1999). Nicoll, G., et al., J. Biol. Chem. 274(48):34089-34095 (1999). |