CSK (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCSK (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis CSK antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 164-197 amino acids from the Central region of human CSK. Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near
Immunogenn/a
Other Names[Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK]
Gene, Accession #[CSK], Gene ID: 1445, NCBI: NP_001120662.1, UniProt: P41240
Catalog #MBS9207906
Price$165, $370
Order / More InfoCSK (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesPartanen J.,et al.Oncogene 6:2013-2018(1991). Braeuninger A.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:10411-10415(1991). Brauninger A.,et al.Gene 110:205-211(1992). Braeuninger A.,et al.Oncogene 8:1365-1369(1993). Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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