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Antigenic Specificity | E-Cadherin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: E-cadherin Polyclonal Antibody detects endogenous levels of E-cadherin protein. CDH1 encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in CDH1 are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human E-cadherin at AA range: 1-80 |
Other Names | [Rabbit E-cadherin; CDH1; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324] |
Gene, Accession # | [CDHE], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830 |
Catalog # | MBS9701931 |
Price | $130, $220, $325 |
Order / More Info | E-Cadherin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |