DNMT3A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDNMT3A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionThe antibody detects endogenous level of total DNMT3A protein. Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development (1,2). Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3 (1,2). DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication. DNMT3A and DNMT3B are strongly expressed in embryonic stem cells with reduced expression in adult somatic tissues. DNMT3A and DNMT3B function as de novo methyltransferases that methylate prev
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human DNMT3A.
Other Names[DNMT3A2; M.HsaIIIA]
Gene, Accession #[DNMT3A], Gene ID: 1788, NCBI: NP_072046.2, UniProt: Q9Y6K1
Catalog #MBS9413269
Price$255
Order / More InfoDNMT3A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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