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Antigenic Specificity | Human Protein BANP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquiti |
Immunogen | Immunogen: Recombinant human Protein BANP protein (460-729aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8132 / sc-8133 / sc-28236 |
Other Names | [BRCA1-associated protein 1; Cerebral protein 6; BAP1; KIAA0272; hucep-6], [BAP1; KIAA0272] |
Gene, Accession # | [BAP1], Gene ID: 8314, NCBI: NP_004647.1, UniProt: Q92560 |
Catalog # | MBS1495232 |
Price | $120, $160 |
Order / More Info | Human Protein BANP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |