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Antigenic Specificity | Toll-like receptor 1 (TLR1) (NT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5) so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells (6) where they form heterodimers that can recognize triacylated lipoproteins (7). |
Immunogen | Immunogen: Rabbit polyclonal TLR1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TLR1. |
Other Names | [Toll-like receptor 1 (NT)], [TLR1] |
Gene, Accession # | [TLR1], NCBI: Q6FI64, UniProt: Q6FI64 |
Catalog # | MBS395916 |
Price | $510 |
Order / More Info | Toll-like receptor 1 (TLR1) (NT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |