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Antigenic Specificity | A1/Bfl-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero-or homodimers and act as anti-and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essen |
Immunogen | Immunogen: Recombinant protein of human BCL2A1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [GRS; BFL1; ACC-1; ACC-2; HBPA1; BCL2L5] |
Gene, Accession # | [A1/Bfl-1], Gene ID: 597, NCBI: NP_001108207.1, UniProt: Q16548 |
Catalog # | MBS8500810 |
Price | $310 |
Order / More Info | A1/Bfl-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |