Phospho-PTPN11 (Y542) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-PTPN11 (Y542) |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426). |
| Immunogen | Immunogen: A synthesized peptide derived from human Phospho-PTPN11 (Y542) |
| Other Names | [Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3; PTPN11; PTP2C; SHPTP2] |
| Gene, Accession # | [PTPN11], Gene ID: 5781, NCBI: NP_001317366.1, UniProt: Q06124 |
| Catalog # | MBS7114888 |
| Price | $185, $265 |
| Order / More Info | Phospho-PTPN11 (Y542) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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