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Antigenic Specificity | Chicken CD5-PE |
Clone | [2-191] |
Host Species | Mouse |
Reactive Species | chicken |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Chicken CD5, Mr 64 kDa (protein core of 57 kDa). Chicken CD5 is a monomeric type I transmembrane glycoprotein whose extracellular region consists of three scavenger receptor cysteine-rich domains. During ontogeny, avian CD5 is first detectable in the thymus and bursa on Embryonic day 10, about 2 to 3 days before the first TCR and surface Ig expression. By the time functional TCR and Ig gene rearrangements and their expression have been completed, all T and B cells in the primary lymphoid organs express CD5. In the periphery, alpha beta T cells express a relatively high level of CD5, whereas a much lower level of the CD5 antigen is detected on gamma delta T cells and B cells. The control of CD5 expression is activation-dependent |
Immunogen | Immunogen: Ed15 thymocytes |
Other Names | [Mouse Chicken CD5 - Phycoerythrin-Labeled; Mouse Chicken CD5], [CD5; CD5; T1; LEU1; LEU1] |
Gene, Accession # | Gene ID: 921, UniProt: P06127 |
Catalog # | MBS673943 |
Price | $285 |
Order / More Info | Chicken CD5-PE Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Koskinen, R., T.W.F. Gobel, C.A. Tregaskes, J.R. Young, and O. Vainio. 1998. The structure of avian CD5 implies aconserved function. J. Immunol. 160:4943-4950. |