AR (Center), 282-309 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAR (Center), 282-309
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: monkey)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.33
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis AR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-309 amino acids from the Central region of human AR. The androgen receptor gene is more than 90 kb long andcodes for a protein that has 3 major functional domains: theN-terminal domain, DNA-binding domain, and androgen-binding domain.The protein functions as a steroid-hormone activated transcriptionfactor. Upon binding the hormone ligand, the receptor dissociatesfrom accessory proteins, translocates into the nucleus, dimerizes,and then stimulates transcription of androgen responsive genes.This gene contains 2 polymorphic trinucleotide repeat segments thatencode polyglutamine and polyglycine tracts in the N
Immunogenn/a
Other Names[Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR; NR3C4]
Gene, Accession #[AR], Gene ID: 367, NCBI: NP_000035.2, UniProt: P10275
Catalog #MBS9211509
Price$165, $370
Order / More InfoAR (Center), 282-309 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesShu, S.K., et al. J. Biol. Chem. 285(43):33045-33053(2010) Nedelsky, N.B., et al. Neuron 67(6):936-952(2010) Panda, B., et al. Gynecol. Endocrinol. (2010) In press : Schneider, G., et al. Am J Geriatr Psychiatry (2010) In press : Guadalupe-Grau, A., et al. PLoS ONE 5 (7), E11529 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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