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Antigenic Specificity | CASP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Immunogen | Immunogen: Recombinant protein of human CASP10 |
Other Names | [ALPS2; FLICE2; MCH4] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: NP_001193453.1, UniProt: Q92851 |
Catalog # | MBS8543921 |
Price | $280 |
Order / More Info | CASP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |