Edit |   |
---|---|
Antigenic Specificity | CIB1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CIB1 antibody detects endogenous levels of total CIB1. Description: The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3).Function: Calcium-binding protein that plays a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac hypertr |
Immunogen | Immunogen: Purified recombinant fragment of human CIB1 expressed in E. Coli Subcellular Location: Membrane. Cytoplasm. Nucleus. Cell Projection > Filopodium. Apical Cell Membrane. Localizes to the perinuclear region in the presence of NBR1. Colocalizes with TAS1R2 in apical regions of taste receptor cells. Tissue Specificity: Detected in platelets and in cell lines of megakaryocytic and erythrocytic lineages. Both isoform 1 and isoform 2 are detected in various cancer cell lines, with isoform 2 |
Other Names | [Calcium and integrin binding 1 (calmyrin); Calcium and integrin binding protein 1; Calcium and integrin-binding protein 1; Calcium-and integrin-binding protein; Calmyrin; CIB; CIB1; CIB1_HUMAN; CIBP; DNA PKcs interacting protein; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; Human Snk interacting protein 2 to 28 mRNA complete cds; Kinase interacting protein; Kinase-interacting protein 1; Kinase-interacting protein; KIP; KIP1; PRKDCIP; SIP2 28; SIP2-28; SNK interacting protein 2 to 28; SNK-interacting protein 2-28] |
Gene, Accession # | [CIB1], Gene ID: 10519, NCBI: NP_001264693.1, UniProt: Q99828 |
Catalog # | MBS9602678 |
Price | $235, $295, $370 |
Order / More Info | CIB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |