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Antigenic Specificity | NOD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NOD2 has no cross-reaction with NOD1. NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease |
Immunogen | Immunogen: Rabbit NOD2 polyclonal antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of human NOD2. Buffer: NOD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NOD2; CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1; Nucleotide-binding oligomerization domain-containing protein 2; Caspase recruitment domain-containing protein 15; nucleotide-binding oligomerization domain containing 2], [NOD2; NOD2; CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1; CARD15; IBD1] |
Gene, Accession # | [NOD2], Gene ID: 64127, NCBI: Q9HC29.1, UniProt: Q9HC29 |
Catalog # | MBS150770 |
Price | $375 |
Order / More Info | NOD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |