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Antigenic Specificity | Human ADAM15 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spli |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | [ADAM15], [ADAM15; ADAM15; MDC15] |
Gene, Accession # | [ADAM15], Gene ID: 8751, NCBI: AAS72298.1 |
Catalog # | MBS415883 |
Price | $230 |
Order / More Info | Human ADAM15 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kuefer,R., Day,K.C., Kleer,C.G., et al. ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease. Neoplasia 8 (4), 319-329 (2006) |