Edit |   |
---|---|
Antigenic Specificity | IL28RA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL28RA antibody detects endogenous levels of total IL28RA. Function: The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infec |
Immunogen | Immunogen: A synthesized peptide derived from human IL28RA Subcellular Location: Membrane; Single-Pass Type I Membrane Protein Tissue Specificity: Widely expressed. Predicted Cross Reactivity: Rabbit, Dog Similarity: Rabbit (88%), Dog (83%) |
Other Names | [Class II cytokine receptor CRF2/12; CRF2-12; CRF2/12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN lambda R1; IFN-lambda receptor 1; IFNLR; IFNLR1; IL-28 receptor subunit alpha; il-28r1; IL28R alpha; IL28RA; Interferon lambda receptor; Interferon lambda receptor 1; interleukin 28 alpha receptor; interleukin 28 receptor A; Interleukin 28 receptor alpha chain; interleukin 28 receptor, alpha (interferon, lambda receptor); Interleukin 28 receptor, alpha; interleukin or cytokine receptor 2; Interleukin-28 receptor subunit alpha; LICR2; Likely interleukin or cytokine receptor 2] |
Gene, Accession # | [IL28RA], Gene ID: 163702, NCBI: NP_734464.1, UniProt: Q8IU57 |
Catalog # | MBS9602967 |
Price | $240, $280 |
Order / More Info | IL28RA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |