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Antigenic Specificity | LSD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LSD1 Antibody: Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is a recently discovered amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues (such as H3-K4) is associated with active transcription. LSD1 associates with various proteins, including HDAC1/2, CoREST, and BHC80, that act to regulate LSD1 activity in vivo, and in a histone H3-K4-specific methylase complex that is involved in transcriptional regulation. Experiment |
Immunogen | Immunogen: LSD1 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human LSD1. Buffer: LSD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [LSD1; AOF2; KDM1; LSD1; BHC110; AOF2; KIAA0601; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; lysine (K)-specific demethylase 1], [KDM1A; KDM1A; AOF2; KDM1; LSD1; BHC110; AOF2; KDM1; KIAA0601; LSD1] |
Gene, Accession # | [KDM1], Gene ID: 23028, NCBI: NP_001009999, UniProt: O60341 |
Catalog # | MBS150364 |
Price | $375 |
Order / More Info | LSD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |