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Antigenic Specificity | MYSM1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, human, rabbit |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MYSM1. It was validated on Western BlotTarget Description: MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYSM1 |
Other Names | [histone H2A deubiquitinase MYSM1; Histone H2A deubiquitinase MYSM1; histone H2A deubiquitinase MYSM1; Myb like, SWIRM and MPN domains 1; Myb-like, SWIRM and MPN domain-containing protein 1] |
Gene, Accession # | [MYSM1], Gene ID: 114803, NCBI: NP_001078956, UniProt: Q5VVJ2 |
Catalog # | MBS3217382 |
Price | $335 |
Order / More Info | MYSM1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |