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Antigenic Specificity | Mafa - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Mafa. It was validated on Western BlotTarget Description: Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context. |
Immunogen | Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse |
Other Names | [transcription factor MafA; Transcription factor MafA; transcription factor MafA; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian); Pancreatic beta-cell-specific transcriptional activator; V-maf musculoaponeurotic fibrosarcoma oncogene homolog A] |
Gene, Accession # | [MAFA], Gene ID: 378435, NCBI: NP_919331, UniProt: Q8CF90 |
Catalog # | MBS3203674 |
Price | $335 |
Order / More Info | Mafa - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |