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Antigenic Specificity | TRF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Telomeric repeat-binding factor 2(TERF2) detection. Background: Telomeric repeat-binding factor 2, also known as TERF2, TRF2, or TRBF2, is encoded in humans by the TERF2 gene. This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. |
Immunogen | Immunogen: E Coli-derived human TRF2 recombinant protein (Position: A81-K287). Human TRF2 shares 95.7% amino acid (aa) sequence identity with mouse TRF2. |
Other Names | [TERF 2; Terf2; TRBF 2; TRBF2; TRF 2; Q15554; Telomeric repeat-binding factor 2], [TERF2; TERF2; TRF2; TRBF2; TRBF2; TRF2] |
Gene, Accession # | [TERF2], Gene ID: 7014, NCBI: NP_005643.2, UniProt: Q15554 |
Catalog # | MBS178617 |
Price | $315 |
Order / More Info | TRF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: TERF2 telomeric repeat binding factor 2.2. Opresko PL, von Kobbe C, Laine JP, Harrigan J, Hickson ID, Bohr VA (October 2002). Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J. Biol. Chem. 277 (43): 41110-9.3. Sakaguchi, A. Y.; Padalecki, S. S.; Mattern, V.; Rodriguez, A.; Leach, R. J.; McGill, J. R.; Chavez, M.; Giambernardi, T. A. (1998-05-01). Chromosomal sublocalization of the transcribed human telomere repeat binding factor 2 gene and comparative mapping in the mouse. Somatic Cell and Molecular Genetics. 24 (3): 157-163. |