S1P1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | S1P1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: At least two isoforms of S1P1 are known to exist; this S1P1 antibody will only recognize the shorter isoform. Movement of lymphocytes through lymphoid organs is required for generating immunity. Their migration into lymph nodes follows a series of events including integrin activation through chemokine signaling, adhesion and diapedis. The release of lymphocytes from lymph nodes is regulated by the phospholipid sphingosine-1-phosphate (S1P). One of its receptors S1P1 binds S1P with high specificity and affinity; agonism of this receptor by the immunosuppressive agent FTY720 inhibits the entry of tissue T cells into afferent lymphatics in homeostatic and inflammatory conditions. Recent experiments have indicated that CCR7-deficie |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the carboxy terminus of the human S1P1. |
| Other Names | [Sphingosine-1-phosphate receptor 1, S1PR1, EDG1, ECGF1] |
| Gene, Accession # | [S1P1], Gene ID: 1901, NCBI: NP_001391 |
| Catalog # | MBS9410370 |
| Price | $320 |
| Order / More Info | S1P1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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