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Antigenic Specificity | c-Myc |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | c-Myc is a phosphoprotein involved with cell proliferation and differentiation. It is a useful marker for differentiation between Burkitt Lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) since, despite morphologically similarities between the two B-cell lymphomas Anti-c-Myc stains all BL and only a few DLBCL cases. A panel of antibodies against c-Myc, CD10, BCL2, and Ki-67 is useful for cases where MYC FISH analysis is warranted or can be omitted. Nuclear c-Myc overexpression is common in luminal cells of prostate intraepithelial neoplasia, many primary carcinomas, and metastatic disease. |
Immunogen | n/a |
Other Names | [c-myc, partial; C-myc protein; myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor], [MYC; c-myc; MRTL; MYCC; c-Myc; bHLHe39] |
Gene, Accession # | [c-Myc], Gene ID: 4609, NCBI: CAA46984.1, UniProt: Q6LBK7 |
Catalog # | MBS344105 |
Price | please inquire |
Order / More Info | c-Myc Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Green TM, et al. Am J Surg Pathol. 2012; 36:612-619. 2. Aukema SM, et al. Blood. 2011l 117:2319-31. 3. Gurel B, et al. Mod Pathol. 2008; 21:1156-67. |