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Antigenic Specificity | IFN-gammaRalpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IFN-gammaRalpha antibody detects endogenous levels of total IFN-gammaRalpha. Function: Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550).Subunit Structure: Monomer (PubMed:9367779). Heterodimer with IFNGR2, to form the IFNG receptor complex (PubMed:7615558). Interacts with JAK1 (PubMed:7615558).Post-translational Modifications: Phosphorylated at Ser/Thr residues.Similarity: Belongs to the type II cytok |
Immunogen | Immunogen: A synthesized peptide derived from human IFN-gammaRalpha Subcellular Location: Membrane. |
Other Names | [Antiviral Protein Type II; Antiviral protein, type 2; AVP type II; AVP, type 2; CD 119; CD119; CD119 antigen; CDw119; FLJ45734; IFN gamma R alpha; IFN gamma R; IFN gamma R1; IFN-gamma receptor 1; IFN-gamma-R1; IFNG R1; IFNGR 1; IFNGR; IFNGR1; Immune interferon receptor 1; Immune interferon receptor for; INGR1_HUMAN; Interferon gamma receptor 1; Interferon gamma receptor alpha chain; Interferon gamma receptor alpha chain precursor] |
Gene, Accession # | [IFNGR1], Gene ID: 3459, NCBI: NP_000407.1, UniProt: P15260 |
Catalog # | MBS9602137 |
Price | $240, $280 |
Order / More Info | IFN-gammaRalpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |