CD59 glycoprotein, Rat Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD59 glycoprotein, Rat |
| Clone | TH9 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), FS, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody TH9 recognizes rat CD59. Rat CD59 was previously known as rat inhibitory protein (RIP) and it is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 regulates the formation and function of the lytic C5b-9 complex by binding C8 and preventing the unfolding and membrane insertion of C9 and by binding C9 and restricting its polymerization.CD59 is a small (18 - 25 kDa) molecule, linked to the cell membrane through a glycosyl phosphatidylinositol (GPI) anchor and comprising 77 amino acids with a single N-linked carbohydrate group at Asn-18. Analogues of CD59 can be found in all species with similar structures and sizes. In rat, CD59 is expressed on vacular endothelium and c |
| Immunogen | Immunogen: Partially purified (FPLC) rat CD59 prep (RIP) |
| Other Names | [Membrane attack complex inhibition factor, MACIF, MAC-inhibitory protein, Protectin, CD59], [CD59; CD59; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; MIC11; MIN1; MIN2; MIN3; MSK21; HRF-20; HRF20; MAC-IP; MACIF; MIRL] |
| Gene, Accession # | [CD59 glycoprotein], Gene ID: 966, NCBI: NP_976076.1 |
| Catalog # | MBS584325 |
| Price | $610 |
| Order / More Info | CD59 glycoprotein, Rat Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hughes, T et al; Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement. Biochem J 1992, 284: 169 2. Hughes, T et al; Immunolocalization and characterization of the rat analogue of human CD59 in kidney and glomerular cells. Immunology. 1993, 80: 439 3. Rogers, C et al; Expression and function of membrane regulators of complement on rat astrocytes in culture. Immunology 1996, 88: 153 |
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MYBIOSOURCE INC.
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