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Antigenic Specificity | GADD153 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GADD153 Antibody detects endogenous levels of GADD153. CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform. |
Immunogen | Immunogen Type: Peptide Immunogen Description: A synthesized peptide derived from human GADD153 |
Other Names | [C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153 Molecular weight: 19174.8 chop] |
Gene, Accession # | [GADD153], Gene ID: 1649, NCBI: NP_001181982.1, UniProt: P35638 |
Catalog # | MBS9409344 |
Price | $255 |
Order / More Info | GADD153 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |