Edit |   |
---|---|
Antigenic Specificity | CRKL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.2 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CRKL protein. This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human v-crk avian sarcoma virus CT10 oncogene homolog-like |
Other Names | [Crk-like protein; CRKL] |
Gene, Accession # | [CRKL], Gene ID: 1399, NCBI: NP_005198.1, UniProt: P46109 |
Catalog # | MBS9411396 |
Price | $255 |
Order / More Info | CRKL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |