ALS2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityALS2
Clonemonoclonal
Host Speciesn/a
Reactive Speciesmouse. Not tested in other organisms
IsotypeIgG1 kappa
Formataffinity purified
Size0.1 mg
Concentration100ug/100ul
ApplicationsWestern Blot (WB)
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DescriptionThis gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen: Recombinant fragment: PSQDLKPVPE RCNQCSQLLI TMTDKEDHVI ISDSHCCPLG VTLTESQAEN HASTALSPST ETLDRQEEVF ENTLVANDQS VATELNAVSA QITSSDAMSS, corresponding to amino acids 221-321 of Human Als2
Other Names[Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) (ALS2), transcript variant 2, mRNA; Alsin; alsin; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; amyotrophic lateral sclerosis 2 protein; amyotrophic lateral sclerosis 2 (juvenile); Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein], [ALS2; ALS2; ALSJ; PLSJ; IAHSP; ALS2CR6]
Gene, Accession #[ALS2], Gene ID: 57679, NCBI: NP_001129217.1
Catalog #MBS415333
Price$330
Order / More InfoALS2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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