Human Plasminogen Activator Inhibitor Type 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Plasminogen Activator Inhibitor Type 1 |
| Clone | polyclonal |
| Host Species | Sheep |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | IgG fraction |
| Size | 10 mg |
| Concentration | IgG concentration is mg/ml, determined by absorbance using an extinction coefficient (E1%280) of 13.4. |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is specific for PAI-1 as demonstrated by immunoelectrophoresis and ELISA. Type I plasminogen activator inhibitor, PAI-1, is a 50 kDa singlechain glycoprotein which belongs to the serine protease inhibitor (SERPIN) family of proteins. The concentration of PAI-1 in normal human plasma is very low, with an average concentration of approximately 20 ng/ml. The plasma concentrations of PAI-1 can be affected by a number of factors including diurnal variations, age, sex, pregnancy, obesity and exercise status. PAI-1 is synthesized by various cell types including endothelial cells, hepatocytes, vascular smooth muscle cells, fibroblasts, mesothelial cells, granulosa cells and malignant cell lines. It is also found in the alpha-granules |
| Immunogen | Immunogen: Recombinant Plasminogen Activator Inhibitor-1 (PAI-1) prepared from bacterial extracts. |
| Other Names | [PAI-1 - Plasminogen Activator Inhibitor type 1, human], [SERPINE1; SERPINE1; PAI; PAI1; PAI-1; PLANH1; PAI1; PLANH1] |
| Gene, Accession # | Gene ID: 5054, NCBI: NP_000593.1, UniProt: P05121 |
| Catalog # | MBS512112 |
| Price | $290 |
| Order / More Info | Human Plasminogen Activator Inhibitor Type 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kruithof, E.K.O. Plasminogen activator inhibitor type 1: biochemical, biological and clinical aspects. Fibrinolysis, 2:59-70, 1988.2. Edelberg, J.M, Sane, D.C., and Pizzo, S.V. Vascular regulation of plasminogen activator inhibitor-1 activity. Semin. Thromb. Hemost., 20(4):319-323, 1994.3. Loskutoff, D.J., Sawdey, M., and Mimuro, J. Type 1 plasminogen activator inhibitor, Prog. Thromb. Haemost., 9:87-115, 1988. |
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MYBIOSOURCE INC.
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