HIPK1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHIPK1
Clonepolyclonal
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatantigen affinity purified
Size0.1 mg
Concentration0.5-1.5 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionOverview: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogene
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 700-750 on human Homeodomain-interacting protein kinase 1 protein. Conjugation: Unconjugated
Other Names[Homeodomain-interacting protein kinase 1; Hipk 1; Homeodomain interacting protein kinase 1; Myak; Nbak 2; Nuclear body associated kinase 2]
Gene, Accession #[HIPK1], Gene ID: 204851, NCBI: NP_689909.2, UniProt: Q86Z02
Catalog #MBS5400416
Price$390
Order / More InfoHIPK1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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