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Antigenic Specificity | SATB2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper- layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections |
Immunogen | Immunogen: A synthesized peptide derived from human SATB2. Subcellular Localization: Nucleus matrix. Tissue Specificity: High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus. |
Other Names | [DNA-binding protein SATB2; Special AT-rich sequence-binding protein 2; SATB2; KIAA1034], [SATB2; SATB2; GLSS; KIAA1034] |
Gene, Accession # | [SATB2], Gene ID: 23314, NCBI: NP_001165980.1, UniProt: Q9UPW6 |
Catalog # | MBS179864 |
Price | $160, $340, $340 |
Order / More Info | SATB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |