CYP19A1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CYP19A1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Aromatase is a member of the cytochrome P450 superfamily of enzymes, which are monooxygenases that catalyze reactions involved in drug metabolism and cholesterol and steroid synthesis (1,2). Aromatase is responsible for the conversion of testosterone into 17beta estradiol (2). Aromatase is mainly expressed in the brain (3), ovaries (4), and placenta (5). Aromatase plays an important role in development of the central nervous system during ontogenesis (6,7), gonadal development, and sex differentiation (8,9). Research studies have suggested that inhibition of aromatase may be an effective therapeutic strategy for postmenopausal breast cancers that are estrogen receptor positive (10,11). Researchers have also linked mutations in aromatase to |
| Immunogen | Immunogen: A synthetic peptide of human CYP19A1 |
| Other Names | [CYP19A1; ARO; ARO1; CPV1; CYAR; CYP19; MGC104309; P450AROM;], [CYP19A1; CYP19A1; ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM; ARO1; CYAR; CYP19] |
| Gene, Accession # | Gene ID: 1588, NCBI: NP_000094.2, UniProt: P11511 |
| Catalog # | MBS127503 |
| Price | $275, $430 |
| Order / More Info | CYP19A1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Harada, N. (1988) Biochem Biophys Res Commun 156, 72532. 2. Chen, S.A. et al. DNA 7, 2738. 3. Hinshelwood, M.M. et al. (2000) Endocrinology 141, 20503. 4. Pezzi, V. et al. (2003) J Steroid Biochem Mol Biol 87, 1819. 5. Peruffo, A. et al. (2011) Gen Comp Endocrinol 172, 2117. 6. Montelli, S. et al. (2012) Brain Res,. 7. Kuntz, S. et al. (2003) Cytogenet Genome Res 101, 2838. 8. Ramsey, M. et al. (2007) Differentiation 75, 97891. 9. Hu, Q. et al. (2012) J Med Chem 55, 70809. 10. Gilani, R.A. et al. (2012) Breast Cancer Res Treat,. 11. Montelli, S. et al. (2012) Brain Res,. 12. Ito, Y. et al. (1993) Proc Natl Acad Sci U S A 90, 116737. 13. Morishima, A. et al. (1995) J Clin Endocrinol Metab 80, 368998. 14. Carani, C. et al. (1997) N Engl J Med 337, 915. 15. Fukami, M. et al. (2012) Int J Endocrinol 2012, 584807. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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