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Antigenic Specificity | ALK, CD246 Mouse |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human; |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Please decide specifity by homology. ALK, also named as CD246, is a receptor tyrosine kinase(RTK) that belongs to the protein kinasesuperfamily. ALK is usually found in the nervous system and appears to play an important role in the normal development and function of the nervous system. ALK was originally identified as part of the NPM(Nucleophosmin)-ALK oncogenic fusion protein, resulting from the(2;5)(p23;q35)translocation that is frequently associated with anaplastic large-cell lymphoma(ALCL). TheEML4(echinoderm microtubule-associated protein-like 4)-ALK fusion protein have been described in non-small-cell lung cancer(NSCLC), this transforming fusion kinase is a promising candidate for a therapeutic target as well as for a d |
Immunogen | Immunogen: Anaplastic lymphoma receptor tyrosine kinase. Calculated MW: 176 kDa |
Other Names | [ALK, ALK tyrosine kinase receptor, ALK,CD246, Anaplastic lymphoma kinase, CD246, TFG/ALK], [ALK; ALK; CD246; NBLST3] |
Gene, Accession # | [ALK, CD246], Gene ID: 238, NCBI: NP_004295.2 |
Catalog # | MBS766542 |
Price | $265 |
Order / More Info | ALK, CD246 Mouse Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |