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Antigenic Specificity | PIASy |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PIASy Polyclonal Antibody detects endogenous levels of PIASy protein. The protein inhibitor of activated Stat (PIAS) proteins, which include PIAS1, PIAS3, PIASx, and PIASy, were originally characterized based on their interaction with the Stat family of transcription factors. PIAS1, PIAS3, and PIASx interact with and repress Stat1, Stat3, and Stat4, respectively. Deletion of PIAS1 leads to inhibition of interferon-inducible genes and increased protection against infection. The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase, coupling the SUMO conjugating enzyme Ubc9 with its substrate proteins. Numerous studies have now shown that PIAS family me |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human PIASy at AA range: 420-500 |
Other Names | [Rabbit PIASy; PIAS4; PIASG; E3 SUMO-protein ligase PIAS4; PIASy; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma; PIAS-gamma] |
Gene, Accession # | [PIASy], Gene ID: 51588, NCBI: NP_056981.2, UniProt: Q8N2W9 |
Catalog # | MBS9706172 |
Price | $130, $220, $325 |
Order / More Info | PIASy Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |