Unc93b Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUnc93b
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: Multiple isoforms of Unc93b are known to exist. This antibody will not cross-react with Unc93a. Unc93b Antibody: The endoplasmic reticulum (ER) protein Unc93b, a human homolog of the C. elegans Unc93 gene, was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3, 7 and 9 signaling. Unlike Unc93a, another homolog of the C. elegans Unc93 gene whose function is unknown, Unc93b specifically interacts with TLR3, 7 and 9; the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction. Mice carrying this point mutation are highly susceptible to infection with a number of viruses, indica
ImmunogenImmunogen: Unc93b antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Unc93b. Buffer: Unc93b Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Unc93b; IIAE1; UNC93; UNC93B; Unc-93B1; Protein unc-93 homolog B1; unc-93 homolog B1 (C. elegans)], [UNC93B1; UNC93B1; IIAE1; UNC93; UNC93B; Unc-93B1; UNC93; UNC93B; Unc-93B1; hUNC93B1]
Gene, Accession #[UNC93B1], Gene ID: 81622, NCBI: AAH33623, UniProt: Q9H1C4
Catalog #MBS150832
Price$375
Order / More InfoUnc93b Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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