DEK Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDEK
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: DEK antibody detects endogenous levels of DEK. Function: Involved in chromatin organization.Subunit Structure: Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK, RBM8A, RNPS1, SRRM1 and ALYREF/THOC4. Interacts with histones H2A, H2B, H3, H4, acetylated histone H4, non-phosphorylated DAXX and HDAC2. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21. Binds DNA.Post-translational Modifications: Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G1 phase, and weakens the binding of DEK to DNA.
ImmunogenImmunogen: A synthesized peptide derived from human DEK. Subcellular Location: Nucleus. Enriched in regions where chromatin is decondensed or sparse in the interphase nuclei. Tissue Specificity: Ubiquitous. Expressed at relatively high levels. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Other Names[D6S231E; Dek; DEK gene; DEK oncogene; DEK oncogene DNA binding; DEK_HUMAN; Protein DEK]
Gene, Accession #[DEK], Gene ID: 7913, NCBI: NP_001128181.1, UniProt: P35659
Catalog #MBS9603325
Price$240, $280
Order / More InfoDEK Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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