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Antigenic Specificity | DEK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DEK antibody detects endogenous levels of DEK. Function: Involved in chromatin organization.Subunit Structure: Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK, RBM8A, RNPS1, SRRM1 and ALYREF/THOC4. Interacts with histones H2A, H2B, H3, H4, acetylated histone H4, non-phosphorylated DAXX and HDAC2. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21. Binds DNA.Post-translational Modifications: Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G1 phase, and weakens the binding of DEK to DNA. |
Immunogen | Immunogen: A synthesized peptide derived from human DEK. Subcellular Location: Nucleus. Enriched in regions where chromatin is decondensed or sparse in the interphase nuclei. Tissue Specificity: Ubiquitous. Expressed at relatively high levels. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%) |
Other Names | [D6S231E; Dek; DEK gene; DEK oncogene; DEK oncogene DNA binding; DEK_HUMAN; Protein DEK] |
Gene, Accession # | [DEK], Gene ID: 7913, NCBI: NP_001128181.1, UniProt: P35659 |
Catalog # | MBS9603325 |
Price | $240, $280 |
Order / More Info | DEK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |