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Antigenic Specificity | GAD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
Immunogen | Immunogen: A synthetic peptide of human GAD2 Calculated Molecular Weight: 65kDa |
Other Names | [GAD2; GAD65], [GAD2; GAD2; GAD65; GAD65; GAD-65] |
Gene, Accession # | [GAD2], Gene ID: 2572, NCBI: Q05329.1, UniProt: Q05329 |
Catalog # | MBS125756 |
Price | $275, $430 |
Order / More Info | GAD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |