LAYN Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-LAYN antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | LAYN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mL |
| Concentration | 0.7 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total LAYN protein. Layilin is a recently cloned 55-kDa membrane-binding partner for talin (Borowsky and Hynes, 1998) that is widely expressed in different cell types and tissue extracts. It is found in peripheral ruffles of spreading cells and is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments. Layilin colocalizes with talin in ruffles and binds to talin's 50-kDa head domain (amino acids 280?C435). Other parts of talin (the 220-kDa tail fragment) can bind b-integrin cytoplasmic tails, vinculin, and F-actin and hence form an integrin-cytoskeleton linkage at sites of cell-substratum contact. Layilin's extracellular domain is homologous with the carbohydrate- |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human layilin |
| Other Names | [FLJ30977; FLJ31092; Layilin; LAYN] |
| Gene, Accession # | [LAYN], Gene ID: 143903, NCBI: NP_001245319.1, UniProt: Q6UX15 |
| Catalog # | MBS9402972 |
| Price | $255 |
| Order / More Info | LAYN Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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