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Antigenic Specificity | DMAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA methylation can help regulate transcriptional silencing via repressive transcription complexes, which include methyl-CpG-binding domain protein and Histone deacetylases DNMT1. This core enzyme for mammalian DNA methylation can also establish a repressive transcription complex consisting of DNMT1, HDAC2 and DMAP1. DMAP1 can interact directly with the transcriptional corepressor TSG101. The DNMT1-DMAP1 exists throughout the S-phase; HDAC2 joind DNMT1 and DMAP1 only during Late S phase. This provides a regulated means to deacetylate heterochromatin following replication |
Immunogen | Immunogen: DMAP1 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 438 of mouse DMAP1 as the immunogen. |
Other Names | [Rabbit DMAP1; DMAP1; DMAP1; DMAP 1; DMAP1; DNMAP1; EAF 2; DMAP-1; DMAP 1; DMAP-1; SWC 4; KIAA1425; FLJ11543; MGC55593; EAF2; SWC4; zgc:55593; DNMAP 1] |
Gene, Accession # | [DMAP1], Gene ID: 55929, UniProt: Q9NPF5 |
Catalog # | MBS5311441 |
Price | $430 |
Order / More Info | DMAP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |