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Antigenic Specificity | GALNS (Center), 236-263 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, porcine, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.48 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GALNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human GALNS. This gene encodes N-acetylgalactosamine-6-sulfatase whichis a lysosomal exohydrolase required for the degradation of theglycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate.Sequence alterations including point, missense and nonsensemutations, as well as those that affect splicing, result in adeficiency of this enzyme. Deficiencies of this enzyme lead toMorquio A syndrome, a lysosomal storage disorder. [provided byRefSeq]. |
Immunogen | n/a |
Other Names | [N-acetylgalactosamine-6-sulfatase; Chondroitinsulfatase; Chondroitinase; Galactose-6-sulfate sulfatase; GalN6S; N-acetylgalactosamine-6-sulfate sulfatase; GalNAc6S sulfatase; GALNS] |
Gene, Accession # | [GALNS], Gene ID: 2588, NCBI: NP_000503.1, UniProt: P34059 |
Catalog # | MBS9209538 |
Price | $165, $370 |
Order / More Info | GALNS (Center), 236-263 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Bank, R.A., et al. Mol. Genet. Metab. 97(3):196-201(2009) Yan, S., et al. Biopolymers 92(5):399-404(2009) Carraresi, L., et al. Clin. Chim. Acta 397 (1-2), 72-76 (2008) : Bhattacharyya, S., et al. J. Biol. Chem. 283(15):9523-9530(2008) |