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Antigenic Specificity | FGD1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1 |
Other Names | [FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain containing 1; Faciogenital dysplasia 1 protein; Rho/Rac guanine nucleotide exchange factor FGD1; Rho/Rac GEF; Zinc finger FYVE domain-containing protein 3] |
Gene, Accession # | [FGD1], Gene ID: 2245, NCBI: NP_004454, UniProt: P98174 |
Catalog # | MBS3200548 |
Price | $335 |
Order / More Info | FGD1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |