FGD1 - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFGD1 - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, horse, human, mouse, porcine, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1
Other Names[FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain containing 1; Faciogenital dysplasia 1 protein; Rho/Rac guanine nucleotide exchange factor FGD1; Rho/Rac GEF; Zinc finger FYVE domain-containing protein 3]
Gene, Accession #[FGD1], Gene ID: 2245, NCBI: NP_004454, UniProt: P98174
Catalog #MBS3200548
Price$335
Order / More InfoFGD1 - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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