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Antigenic Specificity | LDLR - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against LDLR. It was validated on Western BlotTarget Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LDLR |
Other Names | [low-density lipoprotein receptor isoform 6; Low-density lipoprotein receptor; low-density lipoprotein receptor; low density lipoprotein receptor] |
Gene, Accession # | [LDLR], Gene ID: 3949, NCBI: NP_001182732, UniProt: P01130 |
Catalog # | MBS3207309 |
Price | $335 |
Order / More Info | LDLR - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |