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Antigenic Specificity | SLC11A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, horse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SLC11A2 Antibody detects endogenous levels of SLC11A2. Description: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.Post Translational Modifications: Ubiquitinated by WWP2. N-glycosylated.Subunit Structure: Forms a complex with NDFIP1 and NEDD4L, in cortical neurons, in response to iron and colbalt exposure; this interaction leads to ubiquitination by |
Immunogen | Immunogen: A synthesized peptide derived from human SLC11A2. Tissue Specificity: Ubiquitously expressed. Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in spleen, thymus and pancreas. Isoform 3 and isoform 4 are abundantly expressed in duodenum and kidney. |
Other Names | [DCT 1; dct-1; DCT1; Divalent cation transporter 1; Divalent metal transporter 1; DMT 1; DMT-1; DMT1; FLJ37416; Natural resistance associated macrophage protein 2; Natural resistance-associated macrophage protein 2; NRAM2_HUMAN; NRAMP 2; NRAMP2; OK/SW-cl.20; Slc11a2; Solute carrier family 11 (proton coupled divalent metal ion transporters) member 2; Solute carrier family 11 member 2] |
Gene, Accession # | [SLC11A2], Gene ID: 4891, NCBI: NP_000608.1, UniProt: P49281 |
Catalog # | MBS9611491 |
Price | $240, $280 |
Order / More Info | SLC11A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |