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Antigenic Specificity | CDC42 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CDC42 Antibody: CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist. |
Immunogen | Immunogen: CDC42 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDC42. Buffer: CDC42 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [CDC42; G25K; CDC42Hs; Cell division control protein 42 homolog; G25K GTP-binding protein; cell division cycle 42 (GTP binding protein, 25kDa)], [CDC42; CDC42; G25K; CDC42Hs] |
Gene, Accession # | [CDC42], Gene ID: 998, NCBI: NP_001782, UniProt: P60953 |
Catalog # | MBS150094 |
Price | $375 |
Order / More Info | CDC42 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |