TNF Receptor-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNF Receptor-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total TNF receptor-1 protein. Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.Jennifer Adjodha, AACR Meeting Abstracts, Apr 2006; 2006: 1028. Kewu Huang, J Appl Physiol, Apr 2007; 102: 1632 - 1639. Kiyoshi Asada, AACR Meeting Abstracts, Apr 2005; 2005: 202. Elaine K Green,
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human TNF receptor-1.
Other Names[CD120a; TBPI; TNF-RI; TNFAR; TNFR1]
Gene, Accession #[TNF], Gene ID: 7132, NCBI: NP_001056.1, UniProt: P19438
Catalog #MBS9413548
Price$200, $255
Order / More InfoTNF Receptor-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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