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Antigenic Specificity | PSK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein. TAK1 is a mitogen-activated protein kinase kinase kinase that can be activated by TGF-beta, bone morphogenetic protein and other cytokines including IL-1. In vivo activation of TAK1 requires association with TAK1 binding protein 1 (TAB1), which triggers phosphorylation of TAK1. Another adaptor protein, TAB2, links TAK1 with TRAF6 and mediates TAK1 activation upon IL-1 stimulation. Once activated, TAK1 phosphorylates MAPK kinases MKK4 and MKK3/6, which activate p38 MAPK and JNK, respectively. In addition, TAK1 activates the NF-kappaB pathway by interacting with TRAF6 and phosphorylating the NF-kappaB inducing kinase (NIK). |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human PSK2 at AA range: 400-480 |
Other Names | [Rabbit PSK2; TAOK1; KIAA1361; MAP3K16; MARKK; Serine/threonine-protein kinase TAO1; Kinase from chicken homolog B; hKFC-B; MARK Kinase; MARKK; Prostate-derived sterile 20-like kinase 2; PSK-2; PSK2; Prostate-derived STE20-like kinase 2; Thousand and one] |
Gene, Accession # | [PSK2], Gene ID: 57551, NCBI: NP_065842.1, UniProt: Q7L7X3 |
Catalog # | MBS9706548 |
Price | $130, $220, $325 |
Order / More Info | PSK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |