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Antigenic Specificity | GABBR2 (C-term), 861-890 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GABBR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-890 amino acids from the C-terminal region of human GABBR2. The multi-pass membrane protein encoded by this genebelongs to the G-protein coupled receptor 3 family and GABA-Breceptor subfamily. The GABA-B receptors inhibit neuronal activitythrough G protein-coupled second-messenger systems, which regulatethe release of neurotransmitters, and the activity of ion channelsand adenylyl cyclase. This receptor subunit forms an activeheterodimeric complex with GABA-B receptor subunit 1, neither ofwhich is effective on its own. Allelic variants of this gene havebeen associated with nicotine dependence. |
Immunogen | n/a |
Other Names | [Gamma-aminobutyric acid type B receptor subunit 2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20; GABBR2; GPR51; GPRC3B] |
Gene, Accession # | [GABBR2], Gene ID: 9568, NCBI: NP_005449.5, UniProt: O75899 |
Catalog # | MBS9212541 |
Price | $165, $370 |
Order / More Info | GABBR2 (C-term), 861-890 Antibody from MYBIOSOURCE INC. |
Product Specific References | Oblak, A.L., et al. J. Neurochem. 114(5):1414-1423(2010) Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) : |